منابع مشابه
Dmd058883 1656..1662
The clinical development of fedratinib, a Janus kinase (JAK2) inhibitor, was terminated after reports of Wernicke’s encephalopathy in myelofibrosis patients. Since Wernicke’s encephalopathy is induced by thiamine deficiency, investigations were conducted to probe possible mechanisms through which fedratinib may lead to a thiamine-deficient state. In vitro studies indicate that fedratinib potent...
متن کاملOp-brhe150265 1757..1758
SSc is a heterogeneous autoimmune CTD characterized by widespread vasculopathy, formation of autoantibodies and varying degrees of skin and major organ fibrosis [1, 2]. The life-threatening nature of this disease is well depicted by a 5-year mortality of 30 50% in a subset of patients with dcSSc and internal organ involvement. Despite the substantial research over the past decade, the aetiology...
متن کاملJean Marc Gaspard Itard
foundation for his subsequent scientific and philosophical studies. His school career ended at sixteen but the young man spent two more years with his uncle. His father had decided upon a business career for his son and had made arrangement for him to enter a large bank at Marseilles, but the national situation prevented the realization of any such hope for in 1794 France sent out a call to col...
متن کاملDmd052563 1662..1670
Despite increasing recognition of potential untoward interactions between herbal products and conventional medications, a standard system for prospective assessment of these interactions remains elusive. This information gap was addressed by evaluating the drug interaction liability of the model herbal product milk thistle (Silybum marianum) with the CYP3A probe substrate midazolam. The inhibit...
متن کاملDev104422 1757..1766
Multiple cell types involved in the regulation of angiogenesis express Wnt ligands. Although β-catenin dependent and independent Wnt signaling pathways have been shown to control angiogenesis, the contribution of individual cell types to activate these downstream pathways in endothelial cells (ECs) during blood vessel formation is still elusive. To investigate the role of ECs in contributing Wn...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Nouvelles de l'estampe
سال: 2015
ISSN: 0029-4888,2680-4999
DOI: 10.4000/estampe.574